Qepler | summits & conferences | 2nd Annual Pharmaceutical Lyophilization Summit, Berlin, 12-13 February 2020
Event Location:
Berlin, Germany
NH Collection Berlin Friedrichstrasse Friedrichstraße 96
12 February 2020 - 13 February 2020

Conference Overview

Although lyophilization is an old process, it remains to be complex. Today we can see increased trend in aseptic freeze-dried products, including biologics, APIs, nanomaterials and new devices. It makes the lyophilization cycle more complicated. Lyophilization becomes systematic and scientific process.

Pharmaceutical Lyophilization Summit 2020 is a knowledge sharing to showcase best practices in technical and regulatory updates, manufacturing and process development, freeze-dried formulation, testing, monitoring and new products development.

The featured talks on:

  • Latest regulatory updates in lyophilisation. Preparation for the regulatory review and inspection.
  • Lyophilisation process development. Process optimisation, monitoring, and control. Model-based process engineering.
  • Risk-based approaches to design and development of drug delivery systems
  • Lyophilization cycle development, optimisation and improvement: real practical examples.
  • Scale-up development and validation of lyophilization processes.
  • Technology transfer from one lyophilization model to another. Predictive models of lyophilization Process.
  • Media Fill design. Validation of lyoprocess. Requirements. Current trends.
  • QbD and PAT approaches. Space design for lyophilization. QbD aspects and determination of critical process parameters.
  • Continuous freeze drying.
  • Innovations in formulation development.
  • Lyophilized formulation: prediction and optimization of stability.
  • Organic co-solvents and their effect on the formulations.
  • New methods to evaluate moisture and formulation effects on the stability of freeze-dried biologics.
  • Container Closure Integrity Testing.
  • Secondary drying and residual moisture monitoring.
  • Freeze drying of novel products: mAbs, bacterial, viral or gene therapy-based products. Challenges in cycle development. New excipients.
  • Lyophilisation in dual chamber cartridges. Process challenges, design and control.
  • New Developments in materials and devices.
  • Advanced vials and novel vial identification approaches.
  • Automatic loading and unloading technologies and robotics. Reasonable limits of automation. Upgrading possibilities.
  • Controlled nucleation techniques. Recent developments. Challenges. Experimental and stability data. Impact on quality and stability of lyophilized biologics.
  • Wireless Technologies. Wireless multipoint temperature sensors for lyophilization monitoring.
  • Other new innovations in lyophilization applications.

Meet our Speakers

Our Sponsors

For 125 years, the name Pfeiffer Vacuum has served as a guarantee for advanced vacuum technology, high quality vacuum solutions and first-class service.  As the inventor of the turbopump we pioneered innovation and progress in the vacuum industry. Thanks to close collaboration with our customers and our continuous focus on their needs, we constantly optimize and expand our product line. Our portfolio includes vacuum pumps, measurement and analysis equipment, as well as leak testing and CCIT solutions.
Pfeiffer Vacuum
Speaker Sponsor
Biopharma Group - Freeze Drying Equipment & After Sales Support Benchtop, Laboratory & Production Scale Vial Handling Solutions & Aseptic Proccessing Lines Volumetric Powder Fillers (UK & Europe) High Pressure Homogenisers Solvent Evaporators / Concentrators Preparative Chromatography Solutions
Biopharma Group


Allergan - Aptar Pharma - AZBIL TELSTAR TECHNOLOGIES SLU - Baxalta Manufacturing Sàrl - Bayer AG - BB-NCIPD Ltd. - Biopharma Process Systems Ltd - BLAC-BioPharma UG - Boehringer Ingelheim - Datwyler Pharma Packaging International NV - De Montfort University - DendroPharm GmbH - Elm o Sanat University - Freie Universität Berlin - Ghent University - INDICAL BIOSCIENCE GmbH - Janssen - KSHM-Rezonanca - Lek Pharmaceuticals d.d. - Lonza AG - Martin Christ Gefriertrocknungsanlagen GmbH - Masaryk University - MSD - MSD International - Novartis Global Drug Development / Technical Research & Development - Pensatech Pharma - Pfeiffer Vacuum GmbH - Pfizer - PharmaCept GmbH - Polpharma SA - Rhine Waal University - Sanofi - SCHOTT AG - Shire Austria GmbH now part of Takeda - Surface Measurement Systems Ltd. - Takeda - Tempris GmbH - VLB Berlin - West Pharmaceutical Services Deutschland GmbH & Co KG and others.



Bachem AG - Bayer - Bayer Pharmaceuticals - BIOCAD - BioTestLab, Ltd - Boehringer Ingelheim - Boehringer Ingelheim Animal Health - CONTIPRO a.s. - CSL Behring AG - CSLBehring GmbH - Datwyler Pharma Packaging International NV - De Montfort University - Ghent University - GOETHE Biotechnology GmbH - iQ-mobil solutions GmbH/Tempris - Janssen Pharmaceutica NV - Kingston University London - Laboratoire Aguettant - Lonza AG - Lyofal - Martin Christ Gefriertrocknungsanlagen GmbH - MediWound - MSD International - Novartis - Oncomed manufacturing a.s. - Patheon - PIGO srl - Sanofi Pasteur - SFM Medical Devices GmbH - Shire - Skan AG - SP Scientific - Takeda - Takeda GmbH - Takeda Vaccines - UCL School of Pharmacy - Vaxxinova Int. - Weibo Hi-tech Group


Bram Jongen

Datwyler Pharma Packaging International NV

chaired a panel discussion with speakers from Shire, MSD, Bayer, Martin Christ, Boehringer Ingelheim, Ghent University, Lonza and De Montfort University.