Simon Kervyn graduated as a PhD in organic chemistry and materials from the University of Namur, Belgium in 2012. After research stays at National Institute of Materials Sciences in Tokyo and at UCLA, Los Angeles, he worked at the Coatings Research Institute in Belgium.
He is now working for Datwyler as manager materials development. In this position he performs customer’s dedicated research to optimize the selection of rubber components to their applications. Furthermore, he works on the development of coated products for the Datwyler portfolio
The presentation will review the different options to avoid sticky rubber stoppers on lyophilisator shelves at the end of the cycle, namely:
Lyo cake colour, aspect and integrity are fundamental quality control criteria to ensure a safe drug products. However, the lyo cake aspect can change after packaging if, for example, moisture content increase. The drug integrity could also be affected by a potential reaction with leachables from the elastomer stopper.
This talk will review the different elastomeric closure selection criteria to prevent modification of the lyo cake.View Details