Koen Nuyts , Ph.D., Nelson Labs Europe - Qepler Summits And Conferences

Koen Nuyts , Ph.D.

Study Director
Nelson Labs Europe
Antwerp, Belgium
We are a leading, global testing lab specializing in expert advisory and testing solutions for medical device, pharmaceutical, tissue & biologics companies

Koen Nuyts has received his Ph.D. in organic chemistry from the Catholic University of Leuven, Belgium.

He has spent two years as a Marie Curie postdoctoral fellow at Procter & Gamble, Brussels Innovation Center, Belgium, during which he focused on process discovery and development.

Currently, he works at Nelson Labs Europe as study director for Extractables and Leachables projects.

Related Sessions:

Genotoxic Impurities in
Pharmaceuticals Summit 2019

GTI strategies & new methodologies: analysis, in silico & regulations. Challenges & opportunities.
  • 11 Apr 2019
  • Berlin, DE
  • Pharma
Day 2: Friday, 12 April 2019
BLOCK:
CASE STUDY: Interactions of Leachables with Biopharmaceuticals: Combined In-Silico and Experimental Model to Monitor the Potential Impact on Quality and Safety of Therapeutic Proteins.
  • The potential effect of Leachables on the quality and the efficacy of Biopharmaceuticals by chemically modifying the therapeutic protein/peptide product.
  • Impact on the patient’s safety including immunogenicity (as a secondary safety effect of those interactions).
  • How to assess the reactivity of potential leachables
    • Nelson REACT: an in-silico reactivity approach to predict if any of the observed extractables could lead to a chemical interaction.
    • Chemical reactivity tests to actually screen for residual chemical reactivity as predicted by Nelson REACT.
  • Case studies
View Details