Dr. Karlheinz Seyfang

Principal Consultant Pharmaceutical Technology
Harro Höfliger Verpackungsmaschinen GmbH
Allmersbach im Tal, Germany

Karlheinz Seyfang served as head of the business unit Pharma Service for Harro Höfliger GmbH and is now Principal Consultant Pharmaceutical Technology.

Before joining HH he spent 20 years in different positions in the pharmaceutical industry. His experience covers pharmaceutical development, clinical trial supplies, manufacturing and packaging of solid dosage forms. He graduated in Pharmacy from the University of Würzburg, Germany, and received his Ph.D. in pharmaceutical chemistry.

At HH his focus is on powder dosing systems and sensors for dose verification.

Related Sessions:

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Inhaled Drug Delivery
Summit 2019

Assess and harness novel approaches to the development of inhaled drug products for enhanced patient care.

23 May 2019
Berlin, DE
Pharma

Day 2: Friday, 24 May 2019

BLOCK: FORMULATION, DEVELOPMENT & DESIGN.

CASE STUDY: Dosing and process control technologies to cover the wide variety of Dry Powder Inhalers.

Dosing systems to fill DPI have to be adapted to the type of containment to be filled, the dosing range and the powder properties.

The functional principle of the different technologies, the integration into production machines and the requirements regarding powder properties will be described.

To mitigate the risk for under-filling during production, not being detected by statistical in-process controls, systems for the 100% in-line verification of fill weights have been developed.

Three different approaches will be presented.

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